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Pancolitis – Symptoms, Causes, Treatment

Written by Dr.Mary

What is Pancolitis?

This is another name for ulcerative colitis that is an inflammatory disease of the bowel or IBD and causes inflammation that is long lasting in areas of the digestive tract.

Similar to Crohn’s disease, additional common IBD, this condition is incapacitating and occasionally may lead to complications that are life-threatening. Since this is a chronic disorder, indicators normally progress over time, instead of suddenly.

Normally this condition affects the lining of the colon that is innermost. It occurs due to continuous stretches of the colon.

Pancolitis Symptoms

The symptoms of this condition include:

  • Begins in the left colon
  • Often affects the total colon
  • Severe bloody diarrhea
  • Abdominal pains and cramps
  • Significant loss of weight
  • Fatigue

Pancolitis Causes

No one is certain what causes any of the ulcerative colitis diseases, but there is agreement as to what doesn’t cause them. Medical personnel do not believe that this is caused by stress, but stress may often aggravate any symptoms. Rather, the current thinking concentrates on the following:

Immune system

Many scientists believe that a bacterium or virus may initiate these diseases. The digestive system gets inflamed when the immune system attempts to fight off invading pathogen. It is also likely that the inflammation can be triggered from an autoimmune response where the body causes an immune reply even when there is no pathogen present.


Since an individual is most likely to cultivate bowel diseases if there is a sibling or parent with these problems, researchers believe that genetic makeup can play a subsidizing role. But, the majority of individuals who have these types of colon problems do not have a family history.

Pancolitis Treatment

The objective of medical management is first to decrease the irritation that usually triggers the symptoms and signs. In the better circumstances, this will not only lead to relief of symptoms but also to long-standing reduction of the condition. Treatment normally includes either surgery or drug therapy.

Physicians use certain categories of medications to manage inflammation in a variety of methods. But, drugs that work fine for some may not work well for others, so it might take time to find the drugs that work well for an individual.

Anti-inflammatory drugs are usually the 1st step in treatment. They include:

Balsalazide (Colazal), alsalazide (Colazal), Mesalamine (Asacol, Lialda), and olsalazine (Dipentum). These drugs are obtainable in oral forms as well as topical such as suppositories and enemas. These drugs have a tendency to have less side effects than the sulfa medications and are usually tolerated well. The physician might prescribe an arrangement of two forms, such as oral and suppository. Mesalamine may relieve symptoms and signs in more than 90% of individuals.


Sulfasalazine or Azulfidine

These may be effective in decreasing symptoms of bowel disease but have numerous side effects, such as nausea, vomiting, heartburn, diarrhea and headache. This medication should not be taken when there is an allergy to sulfa drugs.


These can help in reducing inflammation but they also have frequent side effects including weight gain, mood swings, excessive hair on the face, bone fractures, glaucoma, cataracts and an increased vulnerability to infections.

Immune system suppressors

These medications decrease inflammation but they aim at the immune system instead of handling inflammation itself. Since immune suppressors may be operational in treating bowel inflammation scientists hypothesize that damage to the digestive soft tissue is produced by the body’s immune response to an occupying virus or bacterium or even to your own tissue.

Additionally to controlling inflammation, some medications can help to relieve symptoms and signs. Depending on the severity of the bowel problem, the physician might recommend one or even more of the following:

  • Antibiotics
  • Anti-diarrheals
  • Pain relievers
  • Iron supplements


If lifestyle changes, diet and drug therapy do not relieve the symptoms and signs, your physician may mention surgery.

Surgery may often eliminate problems with the bowel. But that typically means eliminating the total rectum and colon. Formerly, subsequent to this surgery the patient would wear a small bag over an abdominal opening. But the fairly new technique called “ileoanal anastomosis” removes the necessity for wearing a bag. Rather, the surgeon builds a pouch from the ending of the small intestine. This pouch is then directly attached to the anus. This permits the individual to dismiss waste more customarily, while you might have more numerous movements that are watery or soft since there is no longer a colon to captivate water.

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